If you already have a web host, obtain from them the names of their primary and secondary nameservers. Don't worry if you don't understand what these things mean. Just save the information somewhere. The information can usually be obtained from their FAQs or other documentation on their site, usually under a category like "domain name" or "DNS" or "domain name transfer" and the like. If you can't find it, email them. You'll need the information to point your domain name to your website after you buy your domain. Having said that, if you don't have a web host yet, don't worry. Just read on.

Domain names used in works of fiction have often been registered in the DNS, either by their creators or by cybersquatters attempting to profit from it. This phenomenon prompted NBC to purchase the domain name Hornymanatee.com after talk-show host Conan O'Brien spoke the name while ad-libbing on his show. O'Brien subsequently created a website based on the concept and used it as a running gag on the show.[34]
Sedo is where I bought my domain - over Escrow - and is a global marketplace to buy, sell, and park domain names. They've over 18 million domain names for sale, but the big part is that they're a huge, well-respected company. This may not be important if you're spending $150 on a domain, but in a $15,000+ purchase - which happens in many cases - you will be potentially buying from a foreign entity, that you don't know, and many of them will suggest an escrow payment. This means you put the money in an account owned by a third party that will hold it and only pass it on once the domain has been transferred over into their name (which in this case is what Sedo does). This can be quite disconcerting - but Sedo is well-known and has done many, many deals - and the process is about as full of hand-holding as handing tens or hundreds of thousands of dollars for a domain name can be.

Avoid having numbers in your domain name. People can get confused about whether the numbers is a digit (3) or a word (three). If you want a number in your domain name because there’s a number in your company name, buy both versions (digit and word) and redirect one to the other. Be especially wary about using the number “0” in a domain name as people may see it as the letter “O.”

The root is the upper-most part of the DNS hierarchy, and involves delegating administrative responsibility of “top-level domains”, which are the last segment of a domain name, such as .com, .uk and .nz. Part of our tasks includes evaluating requests to change the operators of country code domains, as well as day-to-day maintenance of the details of the existing operators.
In order to register any domain, you must provide certain personal information that you may not wish to be publically searchable in the Whois database. Signing up for WhoisGuard is a great way to keep your registration data private. WhoisGuard acts as a "shield" for your searchable information, displaying the address, phone number, and email of the domain registrar (Namecheap, e.g.) instead of your own. Keep in mind that WhoisGuard is an optional security add-on that must be renewed separately when you renew your domain.