Even if the term isn’t trademarked, don’t buy domains that are just a variation of another domain name. This means avoiding plurals if the singular is taken (mediatemple.net vs. mediatemples.net), hyphenating a phrase (media-temple.net), or adding “my” or some other preposition (mymediatemple.net). Alternately, you might consider buying these variations yourself and set them up so that if someone types one of the variations, they are redirected to your main site.
For the most part, you can pick whichever TLD you prefer, though a few have restrictions -- you can't buy a .edu domain unless you run an accredited post-secondary school. Many, but not all, country-specific domains (.us, .uk, .jp) are restricted to citizens of the country in question. Unrestricted country domains are often used for "domain hacks," where the extension becomes part of the title, such as YouTube's alternate address, "youtu.be."
Domain names are often seen in analogy to real estate in that domain names are foundations on which a website can be built, and the highest quality domain names, like sought-after real estate, tend to carry significant value, usually due to their online brand-building potential, use in advertising, search engine optimization, and many other criteria.
For special purposes, such as network testing, documentation, and other applications, IANA also reserves a set of special-use domain names. This list contains domain names such as example, local, localhost, and test. Other top-level domain names containing trade marks are registered for corporate use. Cases include brands such as BMW, Google, and Canon.
Domain names used in works of fiction have often been registered in the DNS, either by their creators or by cybersquatters attempting to profit from it. This phenomenon prompted NBC to purchase the domain name Hornymanatee.com after talk-show host Conan O'Brien spoke the name while ad-libbing on his show. O'Brien subsequently created a website based on the concept and used it as a running gag on the show.
A great domain name is a concise, easy to type, and memorable URL that reflects your brand or your website’s subject matter. Avoid using hyphens, strings of numbers, or unnecessary words to make it easy for your visitors to remember and find your website. Remember: A great domain name is one that your visitors can type correctly on their first try.