Avoid having numbers in your domain name. People can get confused about whether the numbers is a digit (3) or a word (three). If you want a number in your domain name because there’s a number in your company name, buy both versions (digit and word) and redirect one to the other. Be especially wary about using the number “0” in a domain name as people may see it as the letter “O.”
My personal preference is to register the name directly with a domain name registrar rather than through my web host. I've heard stories, in the past, of less-than-reputable web hosts that registered the domain under their own name, making them the owner of the domain rather than you (although I don't know if such web hosts still exist today). Registering direct with a domain name registrar allows me to make sure that I am registered as the owner, the administrative and technical contacts. Being the owner is vital — if someone else places himself as the owner (such as your web host), he can always decide to charge you some exorbitant fee for the use of the name later, and there is little you can do. The various other contacts are less vital, but may still play important roles, depending on your registrar. For example, for some registrars, the administrative contact's approval is required before a domain name is transferred out of a web host (or at least, it used to be). If he/she cannot be contacted, the technical contact is used.
Domain names can be used in a number of ways. Direct visitors to your website’s home page or use complementary domains to send them to specific areas of your website ( e.g. yourcompany.jobs for a careers page). Or, forward a custom domain to an existing social media account, like your Twitter profile or Periscope channel. With a domain name you can even set up custom email addresses like email@example.com, which can be used to conduct business or communicate with your followers. More.